A new study shows that the protein CHIP can regulate the insulin receptor more efficiently alone than in a paired state. In cellular stress situations, CHIP usually appears as a homodimer—an association of two identical ...
Cell & Microbiology
Sep 12, 2022
0
85
The initiation of the innate immune responses relies on the detection of microbes by multiple pattern recognition receptors. Among these receptors, cyclic GMP-AMP synthase (cGAS) has been identified as a major and universal ...
Cell & Microbiology
Sep 8, 2022
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4
When we think of plants, the phrase "stressed out" doesn't typically come to mind. They are, after all, exempt from paying bills and tackling existential questions. However, environmental changes—both living (biotic) and ...
Cell & Microbiology
Aug 24, 2022
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38
The immune system of vertebrates is a powerful weapon against external pathogens and cancerous cells. T cells play a crucial role in this context. They carry a special receptor called the T-cell receptor on their surface ...
Cell & Microbiology
Aug 18, 2022
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27
When female mosquitoes are looking for a human to bite, they smell a unique cocktail of body odors that we emit into the air. These odors then stimulate receptors in the mosquitoes' antenna. Scientists have tried deleting ...
Cell & Microbiology
Aug 18, 2022
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53
Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these ...
Biochemistry
Aug 18, 2022
0
39
Recently, scientists from the Chinese Academy of Sciences summarized recent research progress on defense responses of horticultural crops to fungal pathogens and novel strategies to regulate the induction of plant resistance, ...
Cell & Microbiology
Aug 17, 2022
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5
How do signals from outside the cell cause a response inside it? Such outside signals could be hormones or neurotransmitters. To notice them, the cell's surface possesses receptors. One of the key classes of such receptors ...
Cell & Microbiology
Aug 15, 2022
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22
Soil-dwelling nematodes depend on their sophisticated sense of smell for survival, able to distinguish between more than a thousand different scents—but the molecular mechanism behind their olfaction has baffled scientists ...
Plants & Animals
Aug 3, 2022
0
300
A study published in Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids. ...
Biochemistry
Jul 22, 2022
0
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