Using a revolutionary live-cell microscopy technique, an international team of scientist has for the first time observed individual receptors for hormones and drugs working in intact cells.
Biochemistry
Oct 19, 2017
0
190
Researchers at the University of Michigan, Stanford University and biotech company ConfometRx have captured the first cryo-electron microscopy snapshots of a key cellular receptor in action.
Biochemistry
May 24, 2017
2
8
Researchers have developed a light-activated tool to show how drugs need to be adapted to combat type 2 diabetes.
Biochemistry
Apr 11, 2016
1
30
Scientists at The Scripps Research Institute (TSRI) have teamed up with several other institutions and pharmaceutical companies, including the University of Southern California (USC), San Diego's Receptos Inc. and Japanese ...
Biochemistry
Jun 18, 2015
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707
In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. ...
Cell & Microbiology
May 1, 2015
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1083
G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...
Cell & Microbiology
Sep 9, 2014
0
1
(Phys.org) —Researchers have used one of the brightest X-ray sources on the planet to map the 3-D structure of an important cellular gatekeeper known as a G protein-coupled receptor, or GPCR, in a more natural state than ...
General Physics
Dec 31, 2013
0
0
In plants, the growth of organs such as roots, leaves and flowers depends upon the activity of meristems. These reservoir-like compartments hold stem cells, which have the ability to develop into various different cell types.
Biotechnology
Sep 11, 2013
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0
A three-dimensional image of one of the proteins that serves as an on-off switch as it binds to receptors on the surface of a cell suggests there may be a sort of main power switch that could be tripped. These surface receptors ...
Biotechnology
Apr 21, 2013
2
0
(Phys.org)—A research team at Weill Cornell Medical College has solved the 3D crystal structure of a member protein in one of the most important classes of human proteins—the G protein-coupled receptors (GPCRs). These ...
Cell & Microbiology
Feb 27, 2013
0
0
