Circular ribonucleic acids (circRNAs) are a promising platform for gene expression studies as a stable and prevalent ribonucleic acid in eukaryotic cells, which arise from back-splicing. In a new report now published in Nature ...
Prions get mostly bad press, but they may be the keys to controlling protein synthesis in cells.
Molecular & Computational biology
Nov 15, 2021
0
292
The synthesis of proteins in the cell is a key process of life. By this means, the genetic code of the genome is translated into the amino acid sequence of proteins. The process is complex—and has been studied in detail ...
Cell & Microbiology
Feb 23, 2024
0
24
For researchers studying how proteins can cause human disease, knowing precisely where proteins are made within cells and tissues could help them learn about their role in disease and come up with new treatments.
Cell & Microbiology
Jun 30, 2023
0
21
Advances in molecular biology have revealed that pep-tRNAs—nascent polypeptides inside the ribosome that are covalently attached to transfer RNA—are involved in myriad cell functions, including gene expression. All proteins ...
Cell & Microbiology
Jan 31, 2023
0
70
Translation, a process that expresses the genetic information from messenger RNA (mRNA) to protein, is vital to maintain cellular protein homeostasis. To synthesize functional proteins and avoid toxic translation products, ...
Molecular & Computational biology
Dec 20, 2022
0
168
The remarkable effectiveness of mRNA vaccines against SARS-CoV-2 has generated much interest in synthetic mRNA therapeutics for treating and preventing disease. But some basic science questions have remained about whether ...
Cell & Microbiology
Aug 24, 2022
0
65
In new research, Aric N. Rogers, Ph.D., who studies the cellular and molecular mechanisms of aging at the MDI Biological Laboratory in Bar Harbor, Maine, has discovered that muscle may be a protected tissue under conditions ...
Molecular & Computational biology
Nov 23, 2021
0
134
Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists at Tokyo Institute of ...
Cell & Microbiology
Nov 15, 2021
0
26
A research group working at Uppsala University has succeeded in studying 'translation factors' – important components of a cell's protein synthesis machinery—that are several billion years old. By studying these ancient ...
Molecular & Computational biology
Apr 29, 2021
0
42
