A scientist at Karolinska Institutet reports that machine learning can be used to gain insights into molecular events that change the shape of proteins after they are made, regulating their ability to interact with each other. ...
Molecular & Computational biology
Oct 7, 2021
0
19
Active genes do not form clusters and share resources during early development in the fruit fly, according to a new study by New York University and Princeton researchers published in the journal Current Biology.
Molecular & Computational biology
Oct 5, 2021
0
250
Biologists at Cold Spring Harbor Laboratory (CSHL) are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems. Originally created ...
Molecular & Computational biology
Oct 4, 2021
0
83
More than 2 billion people worldwide are fully vaccinated against COVID-19. However, many who live in resource-limited countries haven't been able to get vaccines, partly because these areas lack temperature-controlled shipping ...
Bio & Medicine
Sep 22, 2021
1
3061
A team of researchers working at the Francis Crick Institute has developed a way to find mutations in similar genome regions of cancer samples. In their paper published in the journal Nature Biotechnology, the group describes ...
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
0
30
The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% ...
Cell & Microbiology
Jul 7, 2021
0
20
Proteins have been quietly taking over our lives since the COVID-19 pandemic began. We've been living at the whim of the virus's so-called "spike" protein, which has mutated dozens of times to create increasingly deadly variants. ...
Molecular & Computational biology
Jun 30, 2021
0
226
How can proteins bind DNA in the cell nucleus, where it is present in form of chromatin, tightly wrapped around histones and therefore mostly inaccessible? Recently, several studies began to uncover the various strategies ...
Cell & Microbiology
Jun 29, 2021
0
9
The SARS-CoV-2 papain-like protease (PLpro) plays an essential role in processing viral proteins needed for replication. In addition, the enzyme can cut and inactivate some human proteins important for an immune response. ...
Cell & Microbiology
Jun 9, 2021
0
6
