Prediction of protein disorder from amino acid sequence

Structural disorder is vital for proteins' function in diverse biological processes. It is therefore highly desirable to be able to predict the degree of order and disorder from amino acid sequence. Researchers from Aarhus ...

New gene regulation model provides insight into brain development

In every cell, RNA-binding proteins (RBPs) help tune gene expression and control biological processes by binding to RNA sequences. Researchers often assume that individual RBPs latch tightly to just one RNA sequence. For ...

Structural biology reveals new target to neutralize COVID-19

An international team of researchers have discovered a new and highly conserved site on the SARS-CoV-2 virus that can be neutralized by a specific antibody. Previous studies have reported that antibodies that block the virus ...

Study reveals DNA 'grammar'

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order. This was the finding of a study recently published in Genome Biology by Luca Nanni, Ph.D. student ...

Binding sites for protein-making machinery

ETH Zurich researchers can predict how tightly a cell's protein synthesis machinery will bind to RNA sequences—even when dealing with many billions of different RNA sequences. This binding plays a key role in determining ...

Machine learning reveals recipe for building artificial proteins

Proteins are essential to the life of cells, carrying out complex tasks and catalyzing chemical reactions. Scientists and engineers have long sought to harness this power by designing artificial proteins that can perform ...

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