Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target these specific proteins. ...
Molecular & Computational biology
Sep 7, 2023
0
1
Case Western Reserve University biochemical researchers have identified a new function of a key protein that leads to cancer—a finding they believe could lead to more effective treatments for a range of cancers and other ...
Biochemistry
Aug 31, 2023
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60
RNA has a central role in the cell's protein production. New research shows that RNA can be changed through various chemical modifications, the function of which is unknown to most. The study was carried out by researchers ...
Cell & Microbiology
Aug 25, 2023
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169
Researchers at Yale University, New Haven, have optimized a polymer-based mRNA vehicle for targeted lung delivery and demonstrated the potential of the platform for mucosal vaccination against respiratory pathogens.
In a compost heap, the nematode Caenorhabditis elegans finds a richly laid table: at a length of just one millimeter, the worm feeds on bacteria that decompose organic material. It is essential that the animal avoids sunlight—and ...
Biotechnology
Aug 2, 2023
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4
Raman spectroscopy—a chemical analysis method that shines monochromatic light onto a sample and records the scattered light that emerges—has caused frustration among biomedical researchers for more than half a century. ...
Optics & Photonics
Jul 26, 2023
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55
For decades, structural biologists have been working on cracking the molecular 3D structures of proteins to understand their function. But what if a protein doesn't have a fixed structure? For molecules that keep changing ...
Molecular & Computational biology
Jul 14, 2023
0
17
Plants have the unique ability to regenerate entirely from a somatic cell, i.e., an ordinary cell that does not typically participate in reproduction. This process involves the de novo (or new) formation of a shoot apical ...
Plants & Animals
Jul 7, 2023
0
351
A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes—organisms that ...
Biotechnology
Jun 28, 2023
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1696
To keep their vital functions in balance, many organisms use small snippets of RNA to "silence" messenger RNAs that code for certain proteins. New research from FMI scientists has revealed a molecular hub that integrates ...
Molecular & Computational biology
Jun 27, 2023
0
1
