Researchers decode targets for hundreds of signaling enzymes

When cells in the human body sense a change in the environment, molecules known as kinases can help them respond: these specialized enzymes activate proteins, propagating signals within a cell that ultimately alter its function. ...

Elucidation of proteins controlling the sleep and awake transition

Professor Hiroki Ueda, Assistant Professor Daisuke Tone, Lecturer Koji Ode, and Qianhui Zhang (4th-year graduate student at the time) at the University of Tokyo showed that CaMKIIβ, a predominant protein kinase expressed ...

Looking through MudPIT for protein interactions

The instructions of life encoded in our genes are decoded through the translation into mRNA, which then instructs the synthesis of proteins. Because mRNA translation is an essential process, it is carefully coordinated through ...

Elucidating cellular responses to force

Accumulated evidence suggests that physical force plays an important role in developmental processes of fertilized animal eggs. During embryogenesis, a variety of cell populations actively migrate and change their positions, ...

Researchers use nanotubes to better understand diseases

Researchers in UC's Department of Cancer Biology are collaborating with material scientists from the University of Houston to create and use nanotubes to capture and understand the regulation of proteins involved in a variety ...

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