The human cellular kinome contains over 500 kinases, accounting for almost 2% of all our genes. It is currently impossible to gauge the phosphorylation status, or even phosphorylation potential, of the entire proteome of ...
New simulations by Rice University scientists tell a tale of two taus and how they relate to neurological disease.
Biochemistry
Feb 3, 2020
0
127
The intricate control of cellular metabolism relies on the coordinated and harmonious interplay between the nucleus and mitochondria. On the one hand, mitochondria are the hub for the production of essential metabolites, ...
Cell & Microbiology
Oct 9, 2023
0
37
Metabolic reaction flux change is the final result of interacting regulations by intracellular gene expression, transcriptional regulation, protein level, translation modification, and allosteric effect. However, the regulatory ...
Cell & Microbiology
Jun 20, 2023
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51
Researchers from Osaka University identify a system known as the "GET pathway" as essential for efficient regulation of the numbers of energy-producing mitochondria
Cell & Microbiology
Jan 31, 2023
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273
Each day, millions of biological processes occur in our body at a cellular level. Studying these processes can help us learn more about how cells function, a field that has continued to intrigue researchers. Recently, however, ...
Biochemistry
Sep 30, 2022
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16
Better treatments for some of cancer's deadliest forms could be closer due to a University of California, Irvine-led discovery about how a certain protein is activated in tumor cells. The finding, spearheaded by researchers ...
Cell & Microbiology
Jul 18, 2022
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73
A pioneering study has revealed how cellular compartments (organelles) are able to control how much they interact and cooperate.
Cell & Microbiology
Jan 12, 2022
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31
For cells to assemble into tissues and whole organs, the extracellular matrix (ECM) as well as integrins are required. The ECM forms a kind of extra-cellular protein meshwork; the integrins are surface proteins, which cells ...
Cell & Microbiology
Nov 9, 2020
0
146
Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription.
Molecular & Computational biology
May 2, 2019
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126
