Temperature and dissolved oxygen (DO) can affect a series of physiological and biochemical responses and drive the expression of regulatory genes. When water temperature increases, the solubility of oxygen decreases, leading ...
Plants & Animals
Jan 21, 2022
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18
Proteins are the workers, messengers, managers, and directors of nearly all inter- and intra-cellular functions in our body. So, all advances in biology, pharmaceuticals, and related fields hinge on having a fundamental understanding ...
Molecular & Computational biology
Oct 4, 2021
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6
A fresh new look at an old technique in protein biochemistry has shown that it should be reintroduced to the spectroscopy toolkit.
Molecular & Computational biology
Oct 19, 2020
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11
Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved molecular chaperones. They play an essential role in maintaining protein homeostasis, including facilitating protein folding and degradation, preventing ...
Biochemistry
Jul 27, 2020
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10
A research team led by Dr. Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong (HKU), in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the ...
Cell & Microbiology
Jun 16, 2020
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3
Molecular dynamics simulations (MD) have become a ubiquitous tool in modern life sciences. In these simulations, the interactions between atoms and molecules and their resulting spatial movements are iteratively calculated ...
Cell & Microbiology
Jun 10, 2020
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9
Proteins are widely used in medicine, biology and chemistry. Enhancing their inherent properties by adding functional molecules to their structures is a common and important step in many fields. For example, adding fluorescent ...
Biochemistry
Feb 13, 2020
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7
Misfolded proteins must be promptly eliminated as they can form toxic aggregates in cells. LMU biologists have studied how this process is triggered in mitochondria and identified a general alarm signal that activates it.
Cell & Microbiology
Aug 27, 2019
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7
When Greg Bowman presents a slideshow about the proteins he studies, their 3-D shapes and folding patterns play out as animations on a big screen. As he describes these molecules, it might be easy to miss the fact that he ...
Molecular & Computational biology
Feb 27, 2019
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4
Protein chains typically fold to function. Folding is a complex process and if done correctly leads to a unique functional fold topology for a given protein chain. Other topologies are also possible but are often non-functional ...
Biochemistry
Dec 14, 2018
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8
