Cells have a sophisticated system to control and dispose of defective, superfluous proteins and thus to prevent damage to the body. Dr. Katrin Bagola and Professor Thomas Sommer of the Max Delbrück Center for Molecular Medicine ...
Cell & Microbiology
May 28, 2013
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In a large multidisciplinary project, researchers at Karolinska Institutet have explored different properties of an enzyme family called NUDIX hydrolases. The study, published in Nature Communications, reveals novel insights ...
Biochemistry
Nov 17, 2017
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(PhysOrg.com) -- Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory have obtained the closest look yet of how a gargantuan molecular machine breaks down unwanted proteins in cells, a critical ...
Cell & Microbiology
Aug 2, 2010
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One can often begin to understand a protein's function by identifying its accomplices in the cell. Accordingly, scientists have developed diverse biochemical assays that essentially allow them to go 'fishing' for interaction ...
Cell & Microbiology
Oct 10, 2012
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Enzymes perform very specific functions and require little energy – which is why biocatalysts are also of interest to the chemical industry. In a review article published in the journal Nature Reviews Chemistry, Professor ...
Biochemistry
Aug 20, 2018
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Effective protein engineering can give us control over the generated products inside a cell. However, for many of the biochemical reactions responsible for these products, we don't we don't know the specific protein or enzyme-producing ...
Biotechnology
Mar 27, 2019
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30
Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools ...
Cell & Microbiology
Mar 21, 2024
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51
A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its ...
Biotechnology
Jun 10, 2024
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17
Chemical lesions in the genetic material DNA can have catastrophic consequences for cells, and even for the organism concerned. This explains why the efficient identification and rapid repair of DNA damage is vital for survival. ...
Cell & Microbiology
Aug 27, 2020
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80
Drinking bone broth is a recent diet fad that proponents claim fights inflammation, eases joint pain and promotes gut health. Simmering animal bones in water releases collagen and other proteins into the broth that may have ...
Biochemistry
Jan 16, 2019
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