A 'biomultimeter' to measure RNA and protein production in real-time

Builders of genetic circuits face the same quandary as builders of digital circuits: testing their designs. Yet unlike bioengineers, engineers have a simple and universal testing tool—the multimeter—that they can touch ...

Designer enzyme uses unnatural amino acid for catalysis

University of Groningen chemists have created a new enzyme with an unnatural amino acid as its active centre. They made the enzyme by modifying an antibiotic binding protein which normally acts as a bacterial transcription ...

Researchers discover a new protein fold with a transport tunnel

The protein LIMP-2 is vital for both humans and animals. If it is absent – due, for example, to a hereditary disease – substances of an unknown nature, probably lipids, accumulate in the organism. Up to now, scientists ...

Artificial organelles based on hybrid protein nanoparticles

Compartmentalization is one of the main strategies by which nature allows for control over many biological processes. For the proper functioning of living cells, organelles, small compartments within the cell, are essential. ...

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