Inside the advanced photon source
To see inside Argonne's Advanced Photon Source (APS), all it takes is a little bit of light.
General Physics
Nov 19, 2012
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Page 22 - News tagged with protein enzymes
Location, location, location: Membrane 'residence' gives proteases novel abilities
Johns Hopkins scientists have discovered a new mode of action for enzymes immersed in cellular membranes. Their experiments suggest that instead of recognizing and clipping proteins based on sequences of amino acids, these ...
Cell & Microbiology
Nov 16, 2012
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Study finds how bacteria inactivate immune defenses
A new study by researchers at Imperial College London has identified a way in which Salmonella bacteria, which cause gastroenteritis and typhoid fever, counteract the defence mechanisms of human cells.
Cell & Microbiology
Nov 15, 2012
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Scientists show protein-making machinery can switch gears with a small structural change process
For the past several years, Min Guo, an assistant professor at The Scripps Research Institute, has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process ...
Cell & Microbiology
Nov 15, 2012
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Breakthrough in understanding role of enzyme in disease
Researchers at the University of Dundee have uncovered the mechanism of an important human enzyme that plays a role in the development of debilitating diseases including cancer, dementia and diabetes.
Biochemistry
Oct 30, 2012
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A new glow for electron microscopy
The glowing green molecule known as green fluorescent protein (GFP) has revolutionized molecular biology. When GFP is attached to a particular protein inside a cell, scientists can easily identify and locate it using fluorescence ...
Biotechnology
Oct 22, 2012
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Advanced computer simulations reveal the conformational changes of an enzyme anchoring to its substrate
Pathogenic bacteria bristle with surface proteins that help them to infect their host. From chemical hooks that anchor the bacteria in place to cloaking proteins that hide them from their host's immune system, each protein ...
Biochemistry
Oct 12, 2012
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Monitoring interactions between proteins in their natural environment with intracellular labeling technique
One can often begin to understand a protein's function by identifying its accomplices in the cell. Accordingly, scientists have developed diverse biochemical assays that essentially allow them to go 'fishing' for interaction ...
Cell & Microbiology
Oct 10, 2012
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Iron-sulfur enzymes as candidates for antibiotic development
The iron-sulfur protein IspH plays a central role in the terpene metabolism of several pathogens. The mechanism of the reaction provides an approach for developing new antibiotics, particularly against malaria and tuberculosis. ...
Biochemistry
Oct 9, 2012
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'Promiscuous' enzymes still prevalent in metabolism
Open an undergraduate biochemistry textbook and you will learn that enzymes are highly efficient and specific in catalyzing chemical reactions in living organisms, and that they evolved to this state from their "sloppy" and ...
Biochemistry
Aug 30, 2012
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