Researchers at Karolinska Institutet and SciLifeLab in Sweden describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function. Their ...
Biochemistry
Jun 23, 2022
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61
Understanding why and how chemotherapy resistance occurs is a major step toward optimizing treatments for cancer. A team of scientists including Markus Seeliger, Ph.D., of the Stony Brook Cancer Center and Renaissance School ...
Biochemistry
Jun 21, 2022
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77
A collaborative effort has revealed a new type of triterpene, a group of organic compounds which are an important source of many medicines. Until now, all triterpenes were believed to be derived from squalene, itself a type ...
Biochemistry
Jun 1, 2022
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140
FMI researchers have identified a synthetic protein that dampens the activity of a cellular pathway involved in viral infection. The findings could help to develop drugs that combat viruses such as influenza A and Zika.
Cell & Microbiology
May 11, 2022
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117
Scientists have developed a new technique to accelerate the discovery of cancer-fighting drugs. The technique identifies molecules that can shut down dangerous proteins before they wreak disease-triggering havoc, by blocking ...
Biochemistry
Apr 7, 2022
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85
The number of potential therapeutic targets on the surfaces of human proteins is much greater than previously thought, according to the findings of a new study in the journal Nature.
Molecular & Computational biology
Apr 6, 2022
1
216
A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable ...
Biochemistry
Mar 25, 2022
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24
In a structural analysis that could help inform efforts to develop new drugs for treating a myriad of diseases, RIKEN biologists have shed light on how the interaction between key signaling proteins and their regulatory partners ...
Cell & Microbiology
Mar 15, 2022
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37
The job of a protein hub inside the nucleus of a cell is similar to that of a chef in a kitchen. Both need to manage multiple tasks efficiently for a successful outcome. For the chef, if they spend too much time chopping ...
Cell & Microbiology
Feb 23, 2022
0
34
A new study from the University of Eastern Finland and the University of Tübingen helps to explain what defines how long a drug molecule stays bound to its target.
Molecular & Computational biology
Jan 28, 2022
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11
