Two researchers from Skoltech and McGill University have published a review of the promising research field known as structural proteomics in the journal Chemical Reviews. This field combines protein chemistry and mass spectrometry, ...
Biochemistry
Jan 27, 2022
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57
Protein drugs are widely used as pharmaceutical agents to treat a range of disorders. However, most of these drugs are not very stable and are only retained in the blood circulation for a limited period, which minimizes their ...
Biotechnology
Jan 25, 2022
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16
A mutated protein causes the genetic disease cystic fibrosis. Now, researchers have solved the structure of the protein and how certain drugs bind to it, unveiling their mode of action.
Cell & Microbiology
Jan 7, 2022
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590
Scientists at ETH Zurich have developed a new method to determine how proteins are organized on the surface of cells. Insights gained with the technology could lead to the development of novel drugs to fight cancer.
Cell & Microbiology
Dec 2, 2021
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112
A computational tool allows researchers to precisely predict locations on the surfaces of human and COVID-19 viral proteins that bind with each other, a breakthrough that will greatly benefit our understanding of the virus ...
Molecular & Computational biology
Nov 29, 2021
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32
Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using ...
Biotechnology
Nov 19, 2021
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476
Liposomes may be the unsung heroes of the COVID-19 pandemic. Without the protection of these microscopic vesicles, the delicate strands of messenger RNA (mRNA) that lie at the heart of the Pfizer and Moderna COVID-19 vaccines ...
Bio & Medicine
Nov 15, 2021
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134
Researchers at Weill Cornell Medicine have discovered how drugs can affect various membrane-spanning proteins in addition to their intended target, potentially causing unwanted side effects. The results illuminate one of ...
Molecular & Computational biology
Nov 10, 2021
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26
Scientists at EMBL Hamburg and CSSB have determined the molecular structure of a gut protein that helps us absorb many drugs. This could help to develop drugs that reach target tissues more efficiently.
Molecular & Computational biology
Nov 3, 2021
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70
Supercomputer simulations by RIKEN researchers have revealed how drug binding to a protein target changes as the surrounding environment becomes more cluttered with other proteins. These simulations could help improve drug ...
Biotechnology
Oct 21, 2021
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73
