Tracing water channels in cell surface receptors

G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...

Treating pain by blocking the 'chili-pepper receptor'

Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...

Chemists create nanofibers using unprecedented new method

Researchers from Carnegie Mellon University have developed a novel method for creating self-assembled protein/polymer nanostructures that are reminiscent of fibers found in living cells. The work offers a promising new way ...

New molecule enables quick drug monitoring

Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants. However, current methods are expensive, ...

Team helps cancer treatment drugs get past their sticking point

Potentially valuable drugs slowed down by sticky molecules may get another shot at success. Joint research by the National Institute of Standards and Technology (NIST), Genentech, the University of Delaware and Institut Laue-Langevin ...

Study of proteins in space could yield new drug development

(Phys.org) —Innovative methods of drug discovery do not always take place in an academic laboratory. They may start there, but they can also happen in orbit aboard the International Space Station, as protein crystallization ...

Looking at proteins to make new medicines and better wine

The Human Genome Project was completed in 2003, mapping out all of the genes of the human genome. When the first draft of results were published many were surprised that we had only 24,000 genes. This seemed like an unremarkable ...

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