Researchers have detailed a mechanism in the distinctive corona of COVID-19 that could help scientists to rapidly find new treatments for the virus, and quickly test whether existing treatments are likely to work with mutated ...
Molecular & Computational biology
Feb 19, 2021
0
63
There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called 'checkpoint proteins.' These ...
Bio & Medicine
Feb 2, 2021
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153
As the scientific community continues researching the novel coronavirus, experts are developing new drugs and repurposing existing ones in hopes of identifying promising candidates for treating symptoms of COVID-19.
Biochemistry
Feb 2, 2021
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90
Since the beginning of the pandemic, scientists worldwide have been working intensely to precisely characterize the novel SARS-CoV2 virus. Only by understanding in detail how the virus is constructed and how it replicates ...
Cell & Microbiology
Feb 1, 2021
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540
Many anti-cancer drugs block signals in cancer cells that help degenerated cells to multiply uncontrollably and detach from tissue. For example, blocking the signaling protein FAK, a so-called kinase, causes breast cancer ...
Biochemistry
Jan 28, 2021
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16
A chemical probe molecule—a "first gen" molecule that can be used for drug development—that targets a host cell's protein quality control pathways can dramatically reduce infection by Dengue and Zika viruses. The research ...
Cell & Microbiology
Jan 27, 2021
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35
A new method of identifying molecular targets to fight disease could help accelerate future drug development new Griffith University research published in Scientific Reports has found.
Cell & Microbiology
Jan 27, 2021
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17
PARP inhibitors are recently developed drugs that have shown great promise against some types of ovarian, breast, prostate and pancreatic cancer, but many patients' tumors develop resistance to the drugs. Now researchers ...
Cell & Microbiology
Jan 19, 2021
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24
Researchers from Duke-NUS Medical School in Singapore and Columbia University in the U.S. have solved how Wnt proteins, which play a fundamental role in cell proliferation and differentiation, hitch a ride to travel from ...
Cell & Microbiology
Jan 12, 2021
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32
Scientists have used computer modeling to identify potential 'vulnerable sites' on a key protein found in coronavirus—paving the way for possible new drug treatments in the future.
Cell & Microbiology
Jan 7, 2021
0
131
