They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction is associated with diseases. Although their molecular ...
Biochemistry
Sep 14, 2022
0
24
Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming. One promising new strategy is to use computational ...
Molecular & Computational biology
Sep 6, 2022
2
103
Researchers at TU Dortmund University and Freie Universität Berlin have developed a process for producing new detergents for drug research. The purpose of the new detergents is to separate sensitive proteins from biomembranes ...
Biochemistry
Aug 31, 2022
0
19
Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer. The idea is that, since cancers grow so quickly, chemotherapy ...
Biochemistry
Aug 24, 2022
0
119
Johns Hopkins Medicine researchers say they have evidence to potentially overturn a prevailing belief in a type of important signaling within cells. The mainstream idea is that a single protein receptor molecule—a kind ...
Cell & Microbiology
Aug 19, 2022
0
41
Our many different organ systems are in constant communication with each other. During exercise, for example, muscles send out signals to fat and liver tissue to release their energy sources. While these communication networks ...
Cell & Microbiology
Aug 17, 2022
0
15
Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...
Biochemistry
Aug 16, 2022
0
18
An international team of researchers has developed a method for altering one class of antibiotics, using microscopic organisms that produce these compounds naturally.
Materials Science
Jul 27, 2022
0
87
A study published in Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids. ...
Biochemistry
Jul 22, 2022
0
18
A new technique that can analyze how drug molecules bind to proteins in tissue samples could offer an improved route to drug discovery and development.
Biochemistry
Jul 14, 2022
0
18
