Novel compound interrupts malaria parasite's lifecycle

An international group of researchers has proven that a molecule called TCMDC-135051 can selectively inhibit a protein that is essential to the lifecycle of Plasmodium falciparum, one of the parasites that causes malaria.

Shapeshifting receptors may explain mysterious drug failures

For sugar to taste sweet and for coffee to be stimulating, or even for light to be seen, first they all need to land on a G protein-coupled receptor. Ubiquitous and diverse, these receptors are a cell's chemical detection ...

Caught in the act: Proteins responsible for metastasis

Research by Assoc. Prof. Nurhan Özlü of Koç University Department of Molecular Biology and Genetics and her team, recently published in Molecular & Cellular Proteomics, has uncovered the effects of two proteins in the ...

Researchers develop thermo-responsive protein hydrogel

Imagine a perfectly biocompatible, protein-based drug delivery system durable enough to survive in the body for more than two weeks and capable of providing sustained medication release. An interdisciplinary research team ...

Why transporters really matter for cell factories

In a new study published in PNAS, scientists from The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) explored how different cell membrane transporters impact the production of dicarboxylic acids.

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