X-ray laser sight reveals drug targets

Researchers from the Moscow Institute of Physics and Technology have published a review on serial femtosecond crystallography, one of the most promising methods for analyzing the tertiary structure of proteins. This technique ...

From bugs to drugs

A new study led by Prof Shoumo Bhattacharya has decoded the structure of unique proteins found in tick saliva and created new ones not found in nature, paving the way for a new generation of "Swiss-army knife' anti-inflammatory ...

Snapshots of the flu virus replication machine in action

Researchers from EMBL Grenoble have, for the first time, observed different functional states of the influenza virus polymerase as it is actively transcribing. These results, published in Nature Structural & Molecular Biology, ...

Key acid-activated protein channel identified

Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart ...

Designing biological movement on the nanometer scale

Synthetic proteins have been created that move in response to their environment in predictable and tunable ways. These motile molecules were designed from scratch on computers, then produced inside living cells.

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