The proteasome is the garbage-disposal system of the cell, enzymatically clearing away unwanted proteins. Since this requires the recognition of individual targets within the crowded cellular environment, it is critically ...
Biochemistry
Apr 28, 2011
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The kinase IKK phosphorylates the protein mutated in Huntington's disease to promote its removal and neuron survival, but IKK may be a double-edged sword that increases neurotoxicity in later stages of the disease. The study, ...
Cell & Microbiology
Dec 21, 2009
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(PhysOrg.com) -- Yale University researchers have discovered a set of cellular chaperones needed to assemble a proteasome, the cellular workhorse that recycles proteins and is crucial for the existence of all eukaryotic cells.
Biochemistry
May 28, 2009
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