(Phys.org)—Biological systems are characterized by a form of molecular recycling – and proteins do not escape this fate. In particular, unneeded or damaged proteins biochemically marked for destruction undergo controlled ...
Researchers have uncovered the intricate molecular mechanism used by parasitic phytoplasma bacteria, known for inducing "zombie-like" effects in plants. This detailed revelation opens new horizons for groundbreaking applications ...
Cell & Microbiology
Dec 5, 2023
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4
Biological cells contain in-built "housekeeping" mechanisms for taking care of damaged cellular structures. This includes the ubiquitin‒proteasome system (UPS), which selectively tags unwanted proteins with the ubiquitin ...
Cell & Microbiology
Oct 4, 2023
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8
As sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment. To do so, plants have evolved distinct molecular mechanisms to sense and respond to the environment and ...
Plants & Animals
Apr 28, 2022
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94
Cell proteins damaged by oxygen radicals can be chemically "tagged" for elimination, but an "emergency pathway" bypasses strict protocol and can eliminate even without the need for prior tagging.
Cell & Microbiology
Jan 3, 2022
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118
Scripps Research chemists Hans Renata, Ph.D., and Alexander Adibekian, Ph.D., have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as ...
Biochemistry
Aug 6, 2020
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A novel connection between primordial organisms and complex life has been discovered, as new evidence sheds light on the evolutionary origins of the cell division process that is fundamental to complex life on Earth.
Evolution
Aug 6, 2020
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161
The proteasome is a major proteolytic machine that regulates cellular proteostasis through selective degradation of ubiquitylated proteins. As the maintenance of protein homeostasis is essential to human health, malfunctions ...
Molecular & Computational biology
Apr 27, 2020
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13
To this end, the team identified several thousand proteins, determined their respective amounts in mutant and reference lines and combined the findings with measurements of photosynthetic performance. Their findings were ...
Plants & Animals
Apr 8, 2020
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20
Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which cells sense dysfunction of the proteasome—a cellular component that degrades unneeded or defective proteins—and respond in a previously ...
Molecular & Computational biology
Apr 18, 2019
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