Researchers generate patient-specific cells from thymus organoids

Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells, researchers report March 23 in the journal Stem Cell Reports. The proof-of-concept work provides ...

Rewiring blood cells to give rise to precursors of sperm

Different cell types—say, heart, liver, blood, and sperm cells—possess characteristics that help them carry out their unique jobs in the body. In general, those characteristics are hard-wired. Without intervention, a ...

Sculpting the human body plan in a dish

Although Michelangelo's masterpiece "David" captured the magnificence of the human body—how exactly this exquisite body plan is established during human development has puzzled scientists for more than a century. This has ...

A big step toward producing rhino gametes

To save the northern white rhinoceros from extinction, the BioRescue team is racing to create lab-grown egg and sperm cells of the critically endangered subspecies. The team has now reported a milestone in Science Advances: ...

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