Chemical modifiers tag-team to regulate essential mechanism of life
Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription.
Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription.
Molecular & Computational biology
May 2, 2019
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Accumulated evidence suggests that physical force plays an important role in developmental processes of fertilized animal eggs. During embryogenesis, a variety of cell populations actively migrate and change their positions, ...
Cell & Microbiology
Mar 8, 2019
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4
Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe ...
Biochemistry
Feb 5, 2019
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8
A research group from Kumamoto University, Japan, has discovered a new neurogenic mechanism responsible for brain development. By applying proprietary technology to detect trace proteins in living organisms, they found that ...
Cell & Microbiology
Nov 2, 2018
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21
Fujitsu Laboratories Ltd., the Insight Centre for Data Analytics, a data analytics research institution based in Ireland, and Fujitsu (Ireland) Limited today announced the development of a technology that makes it possible ...
Biochemistry
Oct 31, 2018
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11
It is one of the great ironies of biochemistry: life on Earth could not have begun without water; yet water stymies some chemical reactions necessary for life itself.
Materials Science
Oct 23, 2017
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Genetic studies in mice have identified a molecular mechanism crucial to maintaining egg cells in a dormant state to ensure female fertility. This work by A*STAR identifies a potential method to prevent infertility when the ...
Cell & Microbiology
Apr 5, 2017
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4
Coordinated activities of protein kinases and protein phosphatases ensure phosphorylation homeostasis and amplitude of signaling response, and understandably its imbalance is linked to diseases, such as cancer. Unlike with ...
Biochemistry
Mar 15, 2017
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6
University of Tsukuba-led researchers explored the function of the reprogramming factor KLF4 in production of induced pluripotent stem cells (iPSCs). KLF4 was shown to bind upstream of the Tcl1 target gene, which controls ...
Cell & Microbiology
Mar 8, 2017
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31
Researchers at the University of British Columbia have identified a common ancestral gene that enabled the evolution of advanced life over a billion years ago.
Evolution
Mar 3, 2016
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