DNA 'molecular scissors' discovered

(PhysOrg.com) -- Scientists at the University of Dundee have discovered a protein that acts as a 'molecular scissors' to repair damaged DNA in our cells, a finding which could have major implications for cancer treatments.

Researchers decode targets for hundreds of signaling enzymes

When cells in the human body sense a change in the environment, molecules known as kinases can help them respond: these specialized enzymes activate proteins, propagating signals within a cell that ultimately alter its function. ...

How a protein breaks free to cause deadly cancers

Better treatments for some of cancer's deadliest forms could be closer due to a University of California, Irvine-led discovery about how a certain protein is activated in tumor cells. The finding, spearheaded by researchers ...

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Phosphorylation

Phosphorylation is the addition of a phosphate (PO43-) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes.

Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2009, the Medline database returns nearly 160,000 articles on the subject, largely on protein phosphorylation).

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