Protein phosphorylation is a major posttranslational modification carried out by protein kinases that constitute an integral part of complex signaling networks in eukaryotes. Casein kinase 1 (CK1) is a conserved serine/threonine ...
Plants & Animals
Sep 28, 2023
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19
In a study published in PNAS, the team led by Prof. Zhou Xiaolong and Prof. Wang Enduo from the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of ...
Cell & Microbiology
Sep 6, 2023
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1
Researchers led by Genshiro Sunagawa at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have shown that an animal's stem cells possess the same level of cold resistance as the animal itself.
Plants & Animals
Aug 17, 2023
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1
Metabolic reaction flux change is the final result of interacting regulations by intracellular gene expression, transcriptional regulation, protein level, translation modification, and allosteric effect. However, the regulatory ...
Cell & Microbiology
Jun 20, 2023
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51
Eukaryotes generate the energy for survival through cellular respiration in mitochondria by a process known as the oxidative phosphorylation. In this process, nutrients and oxygen are converted into a chemical form of energy: ...
Cell & Microbiology
Mar 27, 2023
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119
When cells in the human body sense a change in the environment, molecules known as kinases can help them respond: these specialized enzymes activate proteins, propagating signals within a cell that ultimately alter its function. ...
Biochemistry
Feb 18, 2023
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23
Researchers from Osaka University identify a system known as the "GET pathway" as essential for efficient regulation of the numbers of energy-producing mitochondria
Cell & Microbiology
Jan 31, 2023
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273
Extracellular Signal Regulated Kinase (ERK) plays an important role in multiple cell signaling processes, by catalyzing the phosphorylation of a variety of substrates. The enzyme itself is activated by phosphorylation at ...
Molecular & Computational biology
Nov 14, 2022
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1
Professor Hiroki Ueda, Assistant Professor Daisuke Tone, Lecturer Koji Ode, and Qianhui Zhang (4th-year graduate student at the time) at the University of Tokyo showed that CaMKIIβ, a predominant protein kinase expressed ...
Molecular & Computational biology
Oct 26, 2022
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7
A research team affiliated with the Laboratory of Polymeric Materials and Biosorbents at the Federal University of São Carlos (UFSCar) in Araras, São Paulo state, Brazil, has produced and is testing cellulose-based materials ...
Biochemistry
Oct 17, 2022
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90
Phosphorylation is the addition of a phosphate (PO43-) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes.
Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2009, the Medline database returns nearly 160,000 articles on the subject, largely on protein phosphorylation).
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