A host protein phosphatase restricts innate immune signaling

The adaptor proteins STING and MAVS are components of critical pathogen-sensing pathways that induce innate immunity. Phosphorylation of either adaptor results in activation of the type I interferon pathway and excessive ...

The 'yin and yang' of malaria parasite development

Scientists searching for new drug and vaccine targets to stop transmission of one of the world's deadliest diseases believe they are closer than ever to disrupting the life-cycle of this highly efficient parasite.

New research divines structure for class of proteins

(PhysOrg.com) -- Most proteins are shapely, but about one-third of them lack a definitive form, at least that scientists can readily observe. These intrinsically disordered proteins (IDPs) perform a host of important biological ...

Researchers track down new biocatalysts

Phosphate is a key element in many processes in the body and essential for global food production. Researchers at the University of Göttingen have now developed a method to detect new enzymes from the environment that can ...

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