Abnormal levels of stress hormones such as adrenaline and cortisol are linked to a variety of mental health disorders, including depression and posttraumatic stress disorder (PTSD). MIT researchers have now devised a way ...
Bio & Medicine
Apr 13, 2020
0
1229
An international team of researchers has used nanoparticles to deliver a drug—one that previously failed in clinical trials for pain—into specific compartments of nerve cells, dramatically increasing its ability to treat ...
Bio & Medicine
Nov 4, 2019
2
1095
Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins ...
Biochemistry
Apr 5, 2017
0
109
People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery.
Biochemistry
Dec 6, 2023
0
20
Depression, obesity or chronic pain—all of these disorders can be triggered or promoted by stress. In two publications, researchers at TU Darmstadt show new ways of treating stress-related diseases.
Biochemistry
Nov 10, 2023
0
53
In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring ...
Molecular & Computational biology
Jan 12, 2023
0
24
Pain, especially chronic pain, is a common neurological phenomenon. The most common chronic pain conditions include low back pain, arthritis pain, migraine and cancer pain—all of which seriously affect people's physical ...
Biochemistry
Nov 16, 2022
0
94
New substances that activate adrenalin receptors instead of opioid receptors have a similar pain relieving effect to opiates, but without the negative aspects such as respiratory depression and addiction.
Biochemistry
Oct 4, 2022
0
33
Molecules in tarantula venom could be used as an alternative to opioid pain killers for people seeking chronic pain relief.
Biochemistry
Apr 14, 2020
0
6380
A tiny snail may offer an alternative to opioids for pain relief. Scientists at the University of Utah have found a compound that blocks pain by targeting a pathway not associated with opioids. Research in rodents indicates ...
Biochemistry
Feb 20, 2017
12
2827
