Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming. One promising new strategy is to use computational ...
Molecular & Computational biology
Sep 6, 2022
2
103
A new perspective published in Nature Reviews Drug Discovery examines the potential of biomolecular condensates to transform drug discovery. Condensates are membrane-less organelles that form dynamically throughout the cell ...
Biotechnology
Aug 19, 2022
0
9
Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...
Biochemistry
Aug 16, 2022
0
18
Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics. Now, in ACS Central Science, researchers report a new molecule that ...
Molecular & Computational biology
Aug 10, 2022
1
187
Researchers have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.
Molecular & Computational biology
Jul 28, 2022
0
207
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind roadmap detailing how stem cells become sensory interneurons—the cells that enable ...
Cell & Microbiology
Jul 20, 2022
0
120
Creating new chemical compounds, such as new drugs, is not as simple as assembling one of those models with colored balls and sticks you might have seen in a beginning chemistry class. No, it's often a complex process with ...
Analytical Chemistry
May 25, 2022
0
173
The emergence of antibiotic-resistant pathogens and the increasing difficulty in developing new drugs has contributed to global challenges in combating infectious diseases. An extensive bioinformatics survey of around 170,000 ...
Molecular & Computational biology
May 10, 2022
0
48
Every time a new cancer drug is announced, it represents hundreds of researchers spending years behind the scenes working to design and test a new molecule. The drug has to be not only effective, but also as safe as possible ...
Biochemistry
Apr 29, 2022
0
104
Experts from the University of Nottingham have developed new software which combines DNA sequencing and machine learning to help them find where, and to what extent, antibiotic resistant bacteria is being transmitted between ...
Cell & Microbiology
Apr 20, 2022
0
512
