Small but mighty, lysosomes play a surprisingly important role in cells despite their diminutive size. Making up only 1-3% of the cell by volume, these small sacs are the cell's recycling centers, home to enzymes that break ...
Cell & Microbiology
Sep 21, 2022
0
121
Methamphetamine is a stimulant that can be taken as a recreational drug, either by injections or smoking. It is classified as a Class A drug in the UK and its recreational use is criminalized in many countries throughout ...
Analytical Chemistry
Sep 20, 2022
1
10
Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming. One promising new strategy is to use computational ...
Molecular & Computational biology
Sep 6, 2022
2
103
A new perspective published in Nature Reviews Drug Discovery examines the potential of biomolecular condensates to transform drug discovery. Condensates are membrane-less organelles that form dynamically throughout the cell ...
Biotechnology
Aug 19, 2022
0
9
Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...
Biochemistry
Aug 16, 2022
0
18
Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics. Now, in ACS Central Science, researchers report a new molecule that ...
Molecular & Computational biology
Aug 10, 2022
1
187
Researchers have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.
Molecular & Computational biology
Jul 28, 2022
0
207
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind roadmap detailing how stem cells become sensory interneurons—the cells that enable ...
Cell & Microbiology
Jul 20, 2022
0
120
Creating new chemical compounds, such as new drugs, is not as simple as assembling one of those models with colored balls and sticks you might have seen in a beginning chemistry class. No, it's often a complex process with ...
Analytical Chemistry
May 25, 2022
0
173
The emergence of antibiotic-resistant pathogens and the increasing difficulty in developing new drugs has contributed to global challenges in combating infectious diseases. An extensive bioinformatics survey of around 170,000 ...
Molecular & Computational biology
May 10, 2022
0
48
