New spheres of knowledge on the origin of life

The shape of a cell affects its physical and chemical properties. Different cell types have developed different shapes to enable effective functioning. But what shape were the very first cells, as life began to evolve?

Scientists reveal the genetic basis of mitochondrial diseases

Mutations in genes encoding mitochondrial aminoacyl-tRNA synthetases are linked to diverse diseases. However, the precise mechanisms by which these mutations affect mitochondrial function and disease development are not fully ...

Developing tools to visualize DNA repair as never before

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...

Analyzing mushroom DNA to study mutation epistasis

A team of researchers from Skoltech and their Russian and U.S. colleagues have gathered two dozen mushrooms of the species Schizophyllum commune and analyzed their DNA, gaining insights into mutations that cancel the negative ...

Scientists show how bone-bordering cells may help shape a skull

A skull is not one single bone but rather a collection of bone plates joined together early in development. In a study of mice, scientists at the Icahn School of Medicine at Mount Sinai showed how the activity of one gene, ...

Cells' replication of DNA is more 'error-prone' in microgravity

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with ...

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