Getting a step ahead of tuberculosis' drug resistance evolution

In the face of natural selection, genetic mutations set some individuals up for success. A single change to the sequence of a gene can give an organism an advantage—and if that mutation is passed to future generations, ...

CRISPR-Cas9 can generate unexpected, heritable mutations

CRISPR-Cas9, the "genetic scissors," creates new potential for curing diseases, but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that ...

Gene mutation that makes dogs small existed in ancient wolves

Popular belief has been that small dogs, such as Pomeranians and Chihuahuas, exist because once dogs were domesticated, humans wanted small, cute companions. But in the journal Current Biology on January 27, researchers at ...

New insights into the effects of radiation from Chernobyl

Researchers at the University of Stirling have found that animals in lakes closest to the Chernobyl nuclear reactor have more genetic mutations than those from further away, giving new insight into the effect of radiation ...

Comprehensive detection of on- and off-target mutations

Sometimes the smallest action can have unintended consequences, like the proverbial flap of a butterfly's wings. So, when making small changes, it's important to be alert to large effects, such as when using gene editing ...

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