Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. Activation of the stress response is at the epicentre of the ...
Cell & Microbiology
Feb 22, 2019
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2
Scientists have identified a new role for a protein complex at the center of a human genetic disorder called Bardet-Biedl syndrome, or BBS, for which there is currently no cure.
Cell & Microbiology
May 31, 2022
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42
Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 ...
Cell & Microbiology
Apr 7, 2021
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139
In the prelude to cancer, genetic mutations can sometimes lead to the formation of chimeric proteins made from parts of two different proteins that are usually separate.
Cell & Microbiology
Jun 9, 2022
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32
As far as humans are concerned, bacteria can be classified as either harmful, pathogenic bacteria and harmless or beneficial non-pathogenic bacteria. To develop better treatments for diseases caused by pathogenic bacteria, ...
Cell & Microbiology
Jun 25, 2020
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3
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle ...
Biochemistry
Apr 16, 2024
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Research carried out at the Hebrew University of Jerusalem has resulted in a promising approach to help treat Alzheimer's disease in a significant proportion of the population that suffers from a particularly rapid development ...
Biochemistry
Jul 20, 2009
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0
DNA is well known as the blueprint of life, necessary for an organism to facilitate living processes. DNA can be damaged by various factors such as radical metabolites, radiation, and some toxic chemicals. As DNA is a molecule ...
Cell & Microbiology
May 18, 2023
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6
For the first time, researchers have constructed a detailed 3D structure of human SAGA, a 20-piece molecular machine crucial to human life.
Molecular & Computational biology
Nov 23, 2021
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50
When a person is injured, blood clotting is essential. However, once the danger has passed, it is equally essential to stop the clotting response in order to prevent thrombosis, or the obstruction of blood flow by clots. ...
Biochemistry
Oct 2, 2017
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