Using math to predict SARS-CoV-2 protein mutations

Oak Ridge National Laboratory, the University of Tennessee at Chattanooga and Tuskegee University researchers used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate.

Mutation reduces energy waste in plants

To this end, the team identified several thousand proteins, determined their respective amounts in mutant and reference lines and combined the findings with measurements of photosynthetic performance. Their findings were ...

New 3-D method improves the study of proteins

Researchers have developed a new computational method called AGGRESCAN3D which will allow studying the 3D structure of folded globular proteins and substantially improve the prediction of any propensity for forming toxic ...

New discovery reveals how the egg controls sperm entry

After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo. This is according to a new study led by researchers ...

Revealing structural secrets of a key cancer protein

Scientists have breathed new life into the study of a protein with an outsized link to human cancers because of its dangerous mutations, using advanced research techniques to detect its hidden regions.

Worm genetics reveal important pathways for sleep regulation

Although the regulation of sleep—how much, when, and how sleep occurs—is mainly considered to be controlled by the brain, sleep deprivation also affects the body, and signals from the body can affect sleep. However, the ...

Turning silenced cancer genes back into fighters

Working with human colon cancer cells and mice, researchers led by experts at the Johns Hopkins Kimmel Cancer Center say they have successfully blocked the activity of portions of a protein known as UHRF1 and restored the ...

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