Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.
Cell & Microbiology
Sep 26, 2013
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In an advance that will help scientists design and engineer proteins, a team including researchers from SLAC and Stanford has found a way to identify how protein molecules flex into specific atomic arrangements required to ...
Biochemistry
Aug 9, 2013
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RNA editing gives organisms a way to adapt the instructions that their DNA provides for making proteins. Few people would have described RNA editing as a simple process, but a new paper in Nature Communications demonstrates ...
Biotechnology
Aug 1, 2013
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In the past year a group of synthetic proteins called CRISPR-Cas RNA-guided nucleases (RGNs) have generated great excitement in the scientific community as gene-editing tools. Exploiting a method that some bacteria use to ...
Biotechnology
Jun 23, 2013
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Research led by Lawrence Stanton and Prasanna Kolatkar of the A*STAR Genome Institute of Singapore has provided valuable insight into embryonic development. Stanton and Kolatkar teamed up with colleagues in Singapore to determine ...
Cell & Microbiology
Jun 19, 2013
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With mutations, it turns out that context can be everything in determining whether or not they are beneficial to their evolutionary fate.
Evolution
Jun 13, 2013
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What makes one Argonaute a slicer and another one not? Human Argonaute proteins are key players in the gene regulation process known as RNA interference, RNAi. Professor Joshua-Tor's group of Cold Spring Harbor Laboratory ...
Cell & Microbiology
Jun 6, 2013
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Undergoing surgery, even a minor procedure, can be stressful for anyone. But for people who have malignant hyperthermia, a hereditary disease that's triggered by certain drugs used for general anesthesia, it can also be dangerous.
Other
Apr 30, 2013
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The extraordinary level of conservation of the tulip tree (Liriodendron tulipifera) mitochondrial genome has redefined our interpretation of evolution of the angiosperms (flowering plants), finds research in biomed Central's ...
Biotechnology
Apr 14, 2013
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Northwestern Medicine scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure.
Cell & Microbiology
Mar 28, 2013
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