A new way for prevention of pathogenic protein misfolding
Incorrectly folded proteins can cause a variety of diseases. Danish researchers have found a solution for preventing this misfolding.
Incorrectly folded proteins can cause a variety of diseases. Danish researchers have found a solution for preventing this misfolding.
Biochemistry
Jun 9, 2016
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By studying more than 50,000 variants of a jellyfish gene, researchers at the Centre for Genomic Regulation in Barcelona (Spain) have drawn a detailed picture of how changes in that gene affect its function. The study, carried ...
Biotechnology
May 12, 2016
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A group of researchers led by Tomoji Mashimo, Associate Professor, Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University and Kazuto Yoshitomi, Assistant Professor, Mouse Genomics Resource ...
Biotechnology
Mar 24, 2016
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Sometimes so-called synonymous mutations occur in DNA. These do not lead to a change in the protein sequence but which may still have major negative effects on the ability of bacteria to survive. New research from Uppsala ...
Evolution
Feb 17, 2016
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59
All it took was one mutation more than 600 million years ago. With that random act, a new protein function was born that helped our single-celled ancestor transition into an organized multicellular organism.
Cell & Microbiology
Jan 7, 2016
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122
HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges ...
Biochemistry
Jul 1, 2015
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178
Researchers have developed a new computational method called AGGRESCAN3D which will allow studying the 3D structure of folded globular proteins and substantially improve the prediction of any propensity for forming toxic ...
Cell & Microbiology
Apr 27, 2015
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Nowhere is the adage "form follows function" more true than in the folded chain of amino acids that makes up a single protein macromolecule. But proteins are very sensitive to errors in their genetic blueprints. One single-letter ...
Biochemistry
Apr 16, 2015
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Chance events may profoundly shape history. What if Franz Ferdinand's driver had not taken a wrong turn, bringing the Duke face to face with his assassin? Would World War I still have been fought? Would Hitler have risen ...
Evolution
Jun 19, 2014
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(Phys.org) —Evolution is a process that takes place over long periods of time over which genetics and ecology may interact, producing novel phenotypic traits. Researchers previously found that after roughly 31,500 generations ...