Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's ...
Biotechnology
Feb 6, 2018
0
65
University of Oregon scientists theorized that they could manipulate a protein one mutation at a time and predict its evolution. They sought to prove it. And failed.
General Physics
Nov 2, 2017
0
39
When a person is injured, blood clotting is essential. However, once the danger has passed, it is equally essential to stop the clotting response in order to prevent thrombosis, or the obstruction of blood flow by clots. ...
Biochemistry
Oct 2, 2017
0
3
When hemoglobin undergoes just one mutation, these protein complexes stick to one another, stacking like Lego blocks to form long, stiff filaments. These filaments, in turn, elongate the red blood cells found in sickle-cell ...
Cell & Microbiology
Aug 23, 2017
0
7
Garden and potted plants with white spots on their leaves are so popular that they are specially selected for this feature. An international research team has now identified a new mutation in the plant Lotus japonicus which ...
Biotechnology
May 5, 2017
0
6
In recent years, scientists, clinicians and pharmaceutical companies have struggled to find new antibiotics or alternative strategies against multi-drug resistant bacteria that represent a serious public health problem. In ...
Cell & Microbiology
Apr 19, 2017
0
8
Some genetic mutations can cause a virus to flourish. Others make the virus wither away, unable to function normally and reproduce. Yet other genetic mutations only show their hand under certain conditions.
Biochemistry
Mar 31, 2017
0
107
Nothing works without proteins in the body, they are the molecular all-rounders in our cells. If they do not work properly, severe diseases, such as Alzheimer's, may result. To develop methods to repair malfunctioning proteins, ...
Biotechnology
Mar 24, 2017
0
19
Proteins do most of the work inside the human body, supporting the structure, function, regulation, and repair of organs, tissues and cells. Proteins are synthesized as extended chains of amino acids that must fold into intricate ...
Cell & Microbiology
Feb 23, 2017
1
10
Just as a boat can be driven off course by a log in its path, a single, random mutation can send life in a new direction. That scenario, says University of Oregon biochemist Ken Prehoda, illustrates how a random mutation ...
Biochemistry
Nov 16, 2016
0
929
