An evolutionary breakpoint in cell division

Japanese researchers from Osaka University have discovered that the interaction between two proteins, M18BP1/KNL2 and CENP-A, is essential for cell division in various species except for mammals including human.

Study dusts sugar coating off little-known regulation in cells

In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...

Mouse genetic blueprint developed

Researchers have developed a valuable mouse genetic blueprint that will accelerate future research and understanding of human genetics. The international team, led by researchers at the Wellcome Trust Sanger Institute and ...

Learning the alphabet of gene control

Scientists at Karolinska Institutet in Sweden have made a large step towards the understanding of how human genes are regulated. In a new study, published in the journal Cell, they identified the DNA sequences that bind to ...

Bacterial colonization of the lung also depends on the host genome

The lung is by no means a sterile place, as was assumed for a long time. In fact, it actually harbors a diverse microbial ecosystem. We know from previous studies that changes in the lung microbiome are associated with diseases ...

A knockout resource for mouse genetics

An international consortium of researchers report today in Nature that they have knocked out almost 40 per cent of the genes in the mouse genome. The completed resource will power studies of gene activity in models of human ...

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