Researchers at the University of Helsinki, together with researchers from the United States, have discovered a small molecule that inhibits the formation in cells of cytokine proteins that promote inflammation. The mechanism ...
Biochemistry
Jun 7, 2023
0
40
A new "molecular editing" technique from Scripps Research enables chemists to add new elements to organic molecules at locations that were previously out of reach.
Analytical Chemistry
May 31, 2023
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14
Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity. They captured six structures ...
Cell & Microbiology
May 23, 2023
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83
Chemotherapy that does not harm the body, but effectively fights cancer cells: that is the goal of chemist Sylvestre Bonnet and his team. During his Ph.D. research, chemist Xuequan Zhou brought that goal a little closer. ...
Bio & Medicine
May 12, 2023
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113
A new type of drug could provide a way to treat multidrug-resistant bacteria, according to a study published in Nature Communications. Instead of targeting the bacteria directly, the drug blocks key toxins involved in the ...
Cell & Microbiology
Apr 18, 2023
1
67
There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective. Chemists and pharmaceutical scientists are frantically searching for new active substances, ...
Biochemistry
Apr 13, 2023
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38
CycPeptMPDB, a novel database created by Tokyo Tech researchers, focuses on the membrane permeability of cyclic peptides and could accelerate the development of drugs based on these promising compounds. This database was ...
Biochemistry
Apr 5, 2023
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36
Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value. One of these hidden gems is (–)-jerantinine A (JA), a molecule with remarkable anticancer properties, ...
Biochemistry
Mar 23, 2023
0
26
A team of chemists at MIT has found that using peptides instead of DNA fragments to tag small molecules can speed up the drug discovery process. Their research is published in the journal Science.
Cell membranes are barriers that maintain cellular homeostasis, and the intracellular delivery of biologically functional molecules, including peptides, proteins, and nucleic acids to manipulate cellular functions. Conventional ...
Bio & Medicine
Mar 6, 2023
0
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