Pioneering automated proteoform imaging

Investigators led by Neil Kelleher, Ph.D., professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed an automated technique for imaging and identifying proteoforms ...

Mapping enzyme catalysis with metabolic sensing

Enzymes maintain a range of protein sequences and diverse structural forms with activities that far exceed the best chemical catalysts. However, research on engineering them with new and improved features are limited due ...

Physicists propose molecular clock to expose new physics

(Phys.org) —A trio of researchers from Germany, Bulgaria and Russia has proposed the idea of using a molecular clock to determine if the electron-proton mass ratio changes over time. In their paper published in Physical ...

New biology unveiled for fundamental cellular machinery

Cellular communication relies on receptor molecules on the cell surface. The periodic uptake and sorting of these receptors, critical for their degradation or recycling, are governed by an elaborate machinery prominently ...

Researchers discover how cells modulate macropinocytic activity

Macropinocytosis is one of the major pathways by which cells non-selectively internalize extracellular fluids. The laboratory strain Dictyostelium discoideum serves as a valuable model for studying the regulation of macropinocytosis.

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