A new tool to study complex genome interactions

People who owned black-and-white television sets until the 1980s didn't know what they were missing until they got a color TV. A similar switch could happen in the world of genomics as researchers at the Berlin Institute ...

Study examines how DNA damage is repaired by antioxidant enzymes

A typical human cell is metabolically active, roaring with chemical reactions that convert nutrients into energy and useful products that sustain life. These reactions also create reactive oxygen species, dangerous by-products ...

Researchers reveal DNA repair mechanism

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

Structural insight into process of gene regulation

In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One of these is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes ...

Researchers shed new light on the motor of DNA replication

DNA replication is the process whereby cells make an exact copy of their DNA before cell division. A key part of the intricate DNA replication machinery is a molecular motor called CMG, which has the vital task of separating ...

Study reveals new mechanism for DNA folding

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics. Their findings provide new insights into chromosomal ...

Euchromatin is not really open in living cells, shows study

DNA and associated proteins in active regions of the genome are condensed but behave like a viscous liquid at the molecular level. This finding greatly increases our understanding of the physical nature of expressed genome ...

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