A record-long polymer DNA negative

A fragment of a single strand of DNA, built of the nucleobases cytosine and guanine, can be imprinted in a polymer—this has been shown by chemists from Warsaw, Denton and Milan. The resulting artificial negative, with a ...

Researchers study DNA polymerases at the molecular level

Complex biological systems can be described as a network of chemical processes that take place in molecules. The scientists of the "ChemLife" research initiative at the University of Konstanz are working together in an equally ...

Single-cell RNA profiling

An LMU team has improved both the sensitivity and efficiency of a popular method for single-cell RNA sequencing, which yields a molecular fingerprint for individual cells based on their patterns of gene activity.

Genes – way weirder than you thought

Pretty much everyone, at least in societies with access to public education or exposure to media in its various forms, has been introduced to the idea of the gene, but "exposure does not equate to understanding" (see Lanie ...

Supercoil me! The art of knotted DNA maintenance

Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. Researchers now suggest that the DNA propensity to be supercoiled, just ...

Gene loss can prove to be an advantage

During evolution, genes can be created, get mutated or duplicated, and even can get lost. To investigate to what extent gene losses can contribute to different adaptations, scientists from the Max Planck Institute of Molecular ...

Human genome decoded with pocket-sized device

Scientists used a portable device no bigger than a cellphone to sequence the most complete human genome ever assembled with a single technology, according to a study published Monday.

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