(PhysOrg.com) -- The secret to fighting often lethal drug resistant fungal infections is to knock out the bug's molecular chaperone, according to U of T researchers.
Cell & Microbiology
Jul 31, 2009
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Temperature and dissolved oxygen (DO) can affect a series of physiological and biochemical responses and drive the expression of regulatory genes. When water temperature increases, the solubility of oxygen decreases, leading ...
Plants & Animals
Jan 21, 2022
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A research team led by Dr. Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong (HKU), in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the ...
Cell & Microbiology
Jun 16, 2020
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An Aussie eucalypt can 'remember' past exposure to extreme heat, which makes the tree and its offspring better able to cope with future heatwaves, according to new research from Macquarie University.
Plants & Animals
Feb 14, 2019
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Researchers at the University of Freiburg report a mechanism inside cells that transports proteins to the mitochondria. Their research has now been published in the science journal Cell Reports.
Cell & Microbiology
Nov 26, 2018
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Small heat-shock proteins (sHSPs) are molecular chaperones that bind to unfolded proteins to prevent protein aggregation and defend against cellular stress. Mutations in human sHSPs are associated with inherited diseases ...
Biochemistry
Oct 17, 2018
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Researchers from the Center for Molecular Biology of Heidelberg University (ZMBH) and the German Cancer Research Center (DKFZ) have investigated the mode of action of a molecular chaperone vital to protein synthesis. Together ...
Cell & Microbiology
Sep 8, 2017
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Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria and at the University of Cologne, Germany have discovered the molecular basis underlying the patterned folding and assembly of muscle proteins. ...
Cell & Microbiology
Jan 18, 2013
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The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study led by researchers at the University of South Florida has found. Using a cell model, the ...
Biochemistry
Oct 9, 2012
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