New research at the University of Chicago has found that the same machinery used by mammalian cells to drive cellular differentiation also plays a critical role in activating genes in yeast in response to environmental stress.
Cell & Microbiology
Nov 22, 2022
0
68
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn ...
Cell & Microbiology
Apr 30, 2024
0
60
All biological processes in our cells are constantly monitored to prevent the accumulation of defective proteins. In the worst case, such protein clumps can trigger diseases. The synthesis of new proteins is particularly ...
Cell & Microbiology
Jun 20, 2023
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248
Proteins tend to fold wrongly and become defective when exposed to stressors such as heat, oxidation, and pH changes. Accumulation of abnormal proteins contributes to neurodegenerative diseases like Alzheimer's.
Cell & Microbiology
May 11, 2023
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16
Published in the Molecular Cell journal on July 19, a research study out of the Hatters Laboratory showed inappropriate protein aggregation is linked to poor outcomes for cell health and survival—especially in neurons in ...
Cell & Microbiology
Jul 19, 2022
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16
In a new study published in Nature Chemical Biology, researchers at Children's Hospital of Philadelphia (CHOP) have revealed the molecular mechanics of a cell-surface molecule that is a potential immunotherapy target. Using ...
Biochemistry
Jun 20, 2022
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92
Chronic stress caused by changing temperatures, Alzheimer's disease or other diseases and forces is an unavoidable part of life. At the cellular level, the "first responders" to stress are known as molecular chaperones. Yet ...
Plants & Animals
Apr 26, 2021
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240
In the cell nucleus, histones play a crucial role packaging DNA into chromatin. Histones are however very sticky to both DNA and RNA, so to ensure they are transported to the cell nucleus after synthesis and bind to the right ...
Cell & Microbiology
Apr 14, 2021
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18
All life on earth evolved multiple layers and networks of ensuring survival upon catastrophic events. Even cells have their emergency plan: the heat shock response. Triggered by multiple stress stimuli such as heat, toxins, ...
Cell & Microbiology
Feb 5, 2021
0
84
Talk about motherly instincts! Biologists at the University of Iowa have learned that female roundworms can alert their future offspring of dangers they will encounter when born, and the mothers pass on these warnings even ...
Plants & Animals
May 18, 2020
0
80
