A glimpse into the formation of the mitoribosome

SciLifeLab Fellow Alexey Amunts and his team together with researchers from the Czech Academy of Sciences report an assembly intermediate of the ribosome in mitochondria. It reveals 22 associated factors that cooperatively ...

Protein quality control and mitochondria

Protein aggregates are toxic for mitochondrial function, and thus disrupt the supply of chemical energy to their host cells. An LMU team has characterized a protein complex that prevents the build-up of such deposits in the ...

RNA-protein network may explain why melanoma grows more

With five-year survival rates being around 30 percent for patients with distant metastatic disease, cutaneous melanoma is the leading cause of skin cancer-related deaths. The major causes of the low survival rate for melanoma ...

Revolutionary new view of how living cells make energy

Researchers at The University of Western Australia and Harry Perkins Institute of Medical Research have made a fundamental discovery about of the atomic structure and function of the biological 'factories' in cells that make ...

New mitochondrially-derived peptides show what they can do

(Phys.org)—There is a whole lot more to the textbook mitochondrial genome then once was thought. A case in point is a multifunctional peptide named humanin that is dual-encoded deep within 16S ribosomal RNA gene in the ...