Related topics: cells

Decoding protein assembly dynamics with artificial protein needles

Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one. This is exactly what researchers at Tokyo Tech have now accomplished with protein needles. By regulating the tip-to-tip ...

Researchers develop a model of yeast nuclear pore complex

Nuclear pore complexes (NPCs) are massive multi-protein complexes that act as passageways for the transport of molecules into and out of the nucleus. Given their central role in gene expression, growth and development, it ...

Understanding the entry mechanism of SARS-CoV-2 into human cells

The biology of SARS-CoV-2, the virus behind the COVID-19 pandemic, remains partially elusive. Understanding viral mechanisms is a key factor in developing effective treatment strategies against the outbreak. Now, Keesiang ...

Integrated photonics meets electron microscopy

Scientists in Switzerland and Germany have achieved efficient electron-beam modulation using integrated photonics—circuits that guide light on a chip. The experiments could lead to entirely new quantum measurement schemes ...

Old protein, new function: tBID can directly trigger cell death

The protein tBID can trigger programmed cell death (apoptosis) by inducing damage in the energy suppliers of the cells, the mitochondria. Apoptosis is essential for maintaining tissue balance. In addition, apoptosis plays ...

Science fiction revisited: Ramjet propulsion

In science fiction stories about contact with extraterrestrial civilisations, there is a problem: What kind of propulsion system could make it possible to bridge the enormous distances between the stars? It cannot be done ...

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Microscopy

Microscopy is the technical field of using microscopes to view samples or objects. There are three well-known branches of microscopy, optical, electron and scanning probe microscopy.

Optical and electron microscopy involve the diffraction, reflection, or refraction of electromagnetic radiation/electron beam interacting with the subject of study, and the subsequent collection of this scattered radiation in order to build up an image. This process may be carried out by wide-field irradiation of the sample (for example standard light microscopy and transmission electron microscopy) or by scanning of a fine beam over the sample (for example confocal laser scanning microscopy and scanning electron microscopy). Scanning probe microscopy involves the interaction of a scanning probe with the surface or object of interest. The development of microscopy revolutionized biology and remains an essential tool in that science, along with many others including materials science and numerous engineering disciplines.

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