The gut microbiome is so useful to human digestion and health that it is often called an extra digestive organ. This vast collection of bacteria and other microorganisms in the intestine helps us break down foods and produce ...
Cell & Microbiology
Jan 4, 2024
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113
The Clinic for Animal Reproduction, Faculty of Veterinary Medicine, Freie Universitaet Berlin in Germany, has investigated the intensive molecular changes that take place during dog pregnancy.
A research group of 46, led by the University of Utah School of Medicine, reports an innovative new method to analyze 33 enzymes from human carbohydrate metabolism and identify 830 protein-metabolite interactions, including ...
MIT engineers have developed a way to closely track how plants respond to stresses such as injury, infection, and light damage, using sensors made of carbon nanotubes. These sensors can be embedded in plant leaves, where ...
Bio & Medicine
Apr 15, 2020
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1197
Secondary metabolites—the compounds produced by microbes to mediate internal and external messaging, self-defense, and chemical warfare—are the basis for hundreds of invaluable agricultural, industrial, and medical products. ...
Cell & Microbiology
Oct 14, 2019
1
182
DNA molecules are well known as carriers of huge amounts of biological information, and there is growing interest in using DNA in engineered data storage devices that can hold vastly more data than our current hard drives. ...
Biotechnology
Jul 3, 2019
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3
The chemical reactions behind the formation of common metabolites in modern organisms could have formed spontaneously in the earth's early oceans, questioning the events thought to have led to the origin of life.
Biochemistry
Apr 25, 2014
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1
(Phys.org)—Everyone has an internal clock, that mysterious process which controls sleeping and hunger patterns, but now researchers are finding out that because the internal clock also controls metabolism, it would be helpful ...
Van Andel Institute scientists have identified more than 1,000 previously undetected proteins in common metabolite samples, which persist despite extraction methods designed to weed them out.
Molecular & Computational biology
Jul 17, 2024
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0
What species live in this coral reef, and are they healthy? Chemical clues emitted by marine organisms might hold that information. But in underwater environments, invisible compounds create a complex "soup" that is hard ...
Ecology
Jun 7, 2024
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12
Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
Examples of primary metabolites produced by industrial microbiology:
The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.
Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.
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