Related topics: cells

New imaging technique captures ever-changing world of metabolites

(Phys.org) —What would you do with a camera that can take a picture of something and tell you how new it is? If you're Berkeley Lab scientists Katherine Louie, Ben Bowen, Jian-Hua Mao and Trent Northen, you use it to gain ...

Scientists utilise breath and sweat to detect trapped humans

Molecules in their breath, sweat and skin have been used to detect humans in a simulation of a collapsed building, raising the prospect of portable sensors for use in real-life situations, such as the devastating aftermath ...

The bug that lays the golden egg

Among the more peculiar organisms that inhabit our Earth exists a bacterium that turns water-soluble gold into microscopic nuggets of solid gold, scientists said Sunday.

Real-time analysis of metabolic products

Biologists at ETH Zurich have developed a method that, for the first time, makes it possible to measure concentration changes of several hundred metabolic products simultaneously and almost in real time. The technique could ...

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Metabolite

Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.

Examples of primary metabolites produced by industrial microbiology:

The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.

Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.

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