By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks—which drive every cellular process from protein ...
Cell & Microbiology
Oct 28, 2019
0
23
Researchers in Strasbourg, France, have found that mixing two small biomolecules, glyoxylate and pyruvate, in iron-salt-rich water produces a reaction network resembling life's core biochemistry. This discovery provides insight ...
Biochemistry
May 3, 2019
25
1470
A research team led by Dr. Kenneth Verstraete in the Unit for Structural Biology at the VIB-UGent Center for Inflammation Research has unraveled the three-dimensional structure and molecular mechanism of ATP citrate lyase ...
Biochemistry
Apr 3, 2019
0
30
Effective protein engineering can give us control over the generated products inside a cell. However, for many of the biochemical reactions responsible for these products, we don't we don't know the specific protein or enzyme-producing ...
Biotechnology
Mar 27, 2019
0
30
Cyclic imines form a general class of chemical compounds that includes the metabolites of drugs used to treat a wide variety of conditions. β-carboline alkaloids in particular have been extensively studied as medicines, ...
Materials Science
Mar 7, 2019
0
10
Bioinformatics researchers at Heinrich Heine University Düsseldorf (HHU) and the University of California at San Diego (UCSD) are using machine learning techniques to better understand enzyme kinetics and thus also complex ...
Biotechnology
Dec 27, 2018
0
43
Bacteria are increasingly resistant to available antibiotics. A team of chemists from the Technical University of Munich (TUM) have now identified important enzymes in the metabolism of staphylococci. Blocking these enzymes ...
Biochemistry
Nov 16, 2018
0
19
A team from the Institute of Fundamental Biology and Biotechnology of SFU used glycerol and sucrose to simulate the intracellular environment of luminescent bacteria and carried out a number of enzymatic reactions. They hope ...
Biochemistry
Oct 29, 2018
0
13
A new study published in the Metabolic Engineering Journal describes a method based on CRISPR/Cas9, which enables flexible engineering of essential and nonessential enzymes without additional engineering. This has multiple ...
Biotechnology
Aug 22, 2018
0
5
In human cells, vitamins often serve as the precursors of cofactors—non-proteins that are an essential part of enzymes. Among them are the flavins, derived from vitamin B2.
Biochemistry
Apr 25, 2018
0
9
