Researchers reveal new molecular mechanism for Parkinson's disease risk
In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.
In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.
Cell & Microbiology
Jun 23, 2022
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29
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they're needed. As a proof of concept, the ...
Bio & Medicine
Jun 16, 2021
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1306
Researchers at the University of Alberta have uncovered what they say has been the missing puzzle piece ever since the genetic code was first cracked.
Cell & Microbiology
Feb 28, 2024
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224
Proteins in lipid membranes are one of the fundamental building blocks of biological functionality. Lawrence Livermore researchers have figured out how to mimic their role using carbon nanotube porins.
Biochemistry
Jul 7, 2017
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1327
In a compost heap, the nematode Caenorhabditis elegans finds a richly laid table: at a length of just one millimeter, the worm feeds on bacteria that decompose organic material. It is essential that the animal avoids sunlight—and ...
Biotechnology
Aug 2, 2023
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4
Researchers have developed models of bacterial outer membranes that can help develop better antibiotics to fight antibiotic-resistant bacteria.
Biochemistry
Nov 16, 2012
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1
A chemical reaction pathway central to plant biology have been adapted to form the backbone of a new process that converts water into hydrogen fuel using energy from the sun.
Materials Science
Jan 11, 2019
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1044
A multidisciplinary group of engineers and scientists has discovered a new method for water filtration that could have implications for a variety of technologies, such as desalination plants, breathable and protective fabrics, ...
Nanomaterials
Dec 16, 2019
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4921
Each of our cells is surrounded by a complex membrane that functions as a biological border, letting ions and nutrients such as salt, potassium and sugar in and out. The guards are membrane proteins, which do the hard work ...
Materials Science
May 12, 2020
10
406
Scientists from the University of Leeds have taken a crucial step forward in bio-nanotechnology, a field that uses biology to develop new tools for science, technology and medicine.
Bio & Medicine
Oct 8, 2014
3
2
A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. More than half of all proteins interact with membranes.
Biological membranes consist of a phospholipid bilayer and a variety of proteins that accomplish vital biological functions. Structural proteins are attached to microfilaments in the cytoskeleton which ensures stability of the cell. Cell recognition proteins allow cells to identify each other and interact. Such proteins are involved in immune response, for example. Membrane enzymes produce a variety of substances essential for cell function. Membrane receptor proteins serve as connection between the cell's internal and external environments. Finally, transport proteins play an important role in the maintenance of concentrations of ions. These transport proteins come in two forms: carrier proteins and channel proteins. Carrier proteins are involved in using the energy released from ATP being broken down to facilitate active transport and ion exchange. These processes ensure that useful substances are able to enter the cell and that toxic substances are pumped out of the cell.
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