Related topics: protein · cell membrane

Keeping a cell's powerhouse in shape

A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. The results, which also shed light on a hereditary disease of ...

Protein scissors for cellular transport

In many ways, a cell is like a city. Proteins or people do daily work to keep the economy going, and items are imported and exported for trade. Imports are shipped into cells by way of endocytosis. Before reaching their final ...

A microscopic topographic map of cellular function

The flow of traffic through our nation's highways and byways is meticulously mapped and studied, but less is known about how materials in cells travel. Now, a team of researchers at the University of Missouri is challenging ...

Key acid-activated protein channel identified

Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart ...

Designing biological movement on the nanometer scale

Synthetic proteins have been created that move in response to their environment in predictable and tunable ways. These motile molecules were designed from scratch on computers, then produced inside living cells.

Surface protein editing in bacteria

University of Minnesota researchers have discovered this previously unknown signaling pathway that regulates surface proteins on bacteria that can lead to new targets for antibiotics.

New approach for solving protein structures from tiny crystals

Using x-rays to reveal the atomic-scale 3-D structures of proteins has led to countless advances in understanding how these molecules work in bacteria, viruses, plants, and humans—and has guided the development of precision ...

Breaking open the gates of antibiotic resistance

Antibiotic resistance is a major health threat, with about two million people in the US getting an antibiotic-resistant infection per year, according to the Centers for Disease Control and Prevention (CDC). Gram negative ...

Bringing information into the cell

Researchers at the Paul Scherrer Institute (PSI) have elucidated an important part of a signal pathway that transmits information through the cell membrane into the interior of a cell.

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Membrane protein

A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. More than half of all proteins interact with membranes.

Biological membranes consist of a phospholipid bilayer and a variety of proteins that accomplish vital biological functions. Structural proteins are attached to microfilaments in the cytoskeleton which ensures stability of the cell. Cell recognition proteins allow cells to identify each other and interact. Such proteins are involved in immune response, for example. Membrane enzymes produce a variety of substances essential for cell function. Membrane receptor proteins serve as connection between the cell's internal and external environments. Finally, transport proteins play an important role in the maintenance of concentrations of ions. These transport proteins come in two forms: carrier proteins and channel proteins. Carrier proteins are involved in using the energy released from ATP being broken down to facilitate active transport and ion exchange. These processes ensure that useful substances are able to enter the cell and that toxic substances are pumped out of the cell.

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